Lecture 9
Citric Acid bout (Kreb Cycle)
Cellular Respiration
-Large arrive of ATP
Pyruvate from glucose is broken megabucks to CO2 + H2O
-Oxygen is needed as the utmost electron acceptor in ETC
Eukaryotic Cell allow cellular respiration to occur in the mitochondria
1. Citric Acid Cycle ÃÂ Matrix
2. ETC ÃÂ Iner Membrane
2. Stages of fight backion occur in the matrix of mitochondria
1. Pyruvate is broken down into acetyl CoA
2. Citric Acid Cycle
1st Stage of Reactions
1. Pyruvate react with Co enzyme A (CoA)
2. Pyruvate splits into CO2 and a 2- light speed molecule
a) 2-Carbon molecule - Acetyl group
3. Acetyl group will automatically attach to CoA tuneing AcetylCoA
4. advanced energy e` (H+) are transferred to nicotinamide adenine dinucleotide+ to form NADH
(receives cardinal high energy electrons)
*Acetyl CoA enters the second stage of cycle.
second Stage of Reactions:
1.Acetyl CoA donates to the Acetyl group to Oxoloaacetate (OAA) to form Citrate
2. Citrate rearranges itself to form isocitate
3. Isocitate loses a carbon to CO2 and form X-Ketagluterate
NAD+ ÃÂ NADH
4.
x-Ketoglutenate loses its Carbon to CO2 and form Succinate
a) all 3 Carbons from Pyruvate have been released to CO2
b)NAD+ ÃÂ NADH
c) nil is stored in ATP
5. Succinate Is converted into fumerate
a)FAD+
6. Fumerate is converted into Malate
7. Malate is converted into Oxaloacetate (OAA)
NAD+ ÃÂ NADH
Products:
1. 2 CO2
3. 3NADH
3.1FADH2
4.1ATP per Acetyl CoA
a) Each acetyl CoA form an special CO2 and NADH
B Therefore, for each pyruvate supplied for Glycolysis
4NADH ÃÂ 8NADH
1FADH ÃÂ 2FAD
3CO2 ÃÂ 6CO2If you want to get a full essay, order it on our website: Ordercustompaper.com
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